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                <text>The healthcare system’s ability to diagnose and care for people with schizophrenia has
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are now available. However, schizophrenia remains a leading cause of disability and
premature mortality.
The utilization of pharmacological and psychosocial interventions in the healthcare
system, which have the potential to significantly improve the quality of life for people
with schizophrenia, heavily depends on medical professionals completing accurate and
comprehensive assessments of patients’ psychopathologies, cognitive profiles, physical
health statuses and any environmental factors that may influence them.
This Special Issue reprint on schizophrenia, from the Journal of Clinical Medicine,
presents a collection of articles on current approaches to assessment and treatment, as
well as new findings and future perspectives of schizophrenia research and care.
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                <text>Armida Mucci (Ed)</text>
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St. Alban-Anlage 66
4052 Basel, Switzerland</text>
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                <text>Cancer is one of the leading causes of morbidity and mortality in humans today, and the number of people affected by cancer is growing. As a result, the search for new antitumor agents that may be more effective and secure than existing treatments is an ongoing effort. Nature provides a wide range of compounds with a great variety of chemical scaffolds and distinct bioactivity profiles. Indeed, natural products are a rich source of bioactive molecules that, over the years, have found application in the treatment of many diseases, including cancer. Natural products have played an important role in chemotherapy and chemoprevention by providing antitumor drugs such as camptothecin, doxorubicin, paclitaxel, vinblastine, and vincristine, as well as understanding the cellular and molecular mechanisms underlying antitumor activity. Significant advances in natural source isolation and extraction techniques have enabled the identification of novel lead compounds as useful starting points for the generation of optimized molecules with enhanced therapeutic potential via semi-synthetic or synthetic processes. The focus of this Topic is on natural substances derived from plants or animals, as well as their synthetic derivatives, which have been investigated for their ability to counteract cancer progression.</text>
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                <text>Barbara De Filippis (Ed)
Alessandra Ammazzalorso (Ed)
Marialuigia Fantacuzzi (Ed)</text>
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St. Alban-Anlage 66
4052 Basel, Switzerland</text>
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                <text>Current Insights on Lipid-Based Nanosystems 2023</text>
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                <text>Lipid-based nanosystems, including solid lipid nanoparticles (SLN) and nanostructured
lipid carriers (NLC), cationic lipid nanoparticles, nanoemulsions, and liposomes, have
been extensively studied to improve drug delivery through different administration
routes. The main advantages linked to these systems are the ability to protect, transport,
and control the release of lipophilic and hydrophilic molecules (either small molecular
weight or macromolecules); the use of generally recognized as safe (GRAS) excipients
that minimize the toxicity of the formulations; and the possibility to modulate
pharmacokinetics and enable the site-specific delivery of encapsulated payloads. In
addition, the versatility of lipid-based nanosystems has been further demonstrated
through the delivery of vaccines, protection of cosmetic actives, or improvement in the
moisturizing properties of cosmetic formulations.
Currently, lipid-based nanosystems are well established, and there are already different
commercially approved formulations for different human disorders. This success has
actually paved the way to diversifying the pipeline of development, upon addressing
unmet medical needs for several indications, such as cancer; neurological disorders; and
autoimmune, genetic, and infectious diseases.
This Special Issue aims to update readers on the latest research on lipid-based
nanosystems, both at the preclinical and clinical levels</text>
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                <text>Ana Catarina Silva (Ed)
Jo ˜ao Nuno Moreira (Ed)
Jos ´e Manuel Sousa Lobo (Ed)</text>
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St. Alban-Anlage 66
4052 Basel, Switzerland</text>
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                <text>The book as a whole is distributed by MDPI under the terms
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doi.org/10.3390/books978-3-0365-9805-5</text>
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                <text>In this Special Issue, recent advancements in the field of pediatric tumors are discussed,
and novel prognostic markers are critically appraised. Greater understanding of the
heterogeneity of pediatric cancers will ultimately lead to new therapeutic strategies with
the potential to provide new prospects for precision medicine in pediatric oncology.
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Emmanouel Hatzipantelis (Ed)
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