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                <text>Pain Management in Clinical and Health Psychology</text>
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                <text>Chronic pain is a relevant health problem frequently associated with psychological distress, dysfunctions in physical and social functioning, reductions in quality of life and elevated direct and indirect costs. Medical approach is typically useful for treating chronic pain, but also psychological contributions play an important role in pain management. In fact psychological treatments are recognized as generally effective for pain. Psychological approaches in managing pain have evolved considerably and now understanding and managing the cognitions, emotions and behaviors that accompany the situation of discomfort can actually reduce the pain intensity and the interference of pain with daily life. Psychological therapies are highly indicated both for the treatment of painful conditions and for the treatment of pain related to several neurological diseases. The reviews and meta-analyses conducted to evaluate the effectiveness of different forms of psychotherapy across several disorders, although with different levels of experimental evidence, confirmed that psychological interventions can improve the experience of patients at every age (children, adolescents, adults, seniors). Similar positive results about psychotherapy efficacy were reported in specific pain disorders such as low back pain, fibromyalgia, tension-type headache and migraine, pain associated with rheumatoid arthritis, chronic abdominal pain in adolescents, chronic orofacial pain, etc. Clinical health psychology focuses also on the study of the psychological determinants in pain patients such as the role of depression, anxiety, pain-related disability, catastrophic thinking, psychological inflexibility, coping skills, beliefs, attitudes, expectations, self-efficacy, placebo and nocebo effects, etc. Different psychological models of pain and disability (such as Fear-avoidance, Acceptance and commitment, Misdirected problem solving, Self-efficacy and Stress-diathesis models) have tried to highlight the psychological processes behind pain. The major objective of the present Research Topic is to collect new scientific evidence, clinical experiences, reviews and opinion articles about clinical health psychology and psychotherapy in pain management and treatment. Moreover this RT will focus on psychological factors, basic psychological processes and theoretical models that could have an impact in the development of persistent pain and disability and implications for different therapies, considering psychological interventions in peri-operative pain and/or preventive interventions in sub-acute pain too.</text>
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                <text>Gianluca Castelnuovo&#13;
Karlein M.G. Schreurs</text>
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                <text>https://directory.doabooks.org/handle/20.500.12854/55563</text>
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                <text>Eastern Philosophies and Psychology: Towards Psychology of Self-Cultivation</text>
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                <text>The publication of this book, East Asian Philosophies and Psychology: Towards Psychology of Self-cultivation, signifies an important breakthrough for the indigenization movements of psychology which have happened in many non-Western countries since 1980s. Viewing from the perspective of scientific revolution (Kuhn, 1969), when Western paradigms of psychology are transplanted to non-Western countries and encounter anomalies which cannot be explained by the imported theories, the foreign theories are in a state of crisis waiting for scientific revolution.</text>
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                <text>Kin-Tung Yit&#13;
Yung-Jong Shiah&#13;
Kwang-Kuo Hwang</text>
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                <text>https://directory.doabooks.org/handle/20.500.12854/45651</text>
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                <text>Features of Pathogenesis of Human Viral Infections and Antiviral Drugs</text>
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                <text>Pathogenesis &#13;
Infections&#13;
Antiviral Drugs&#13;
Drugs&#13;
Medicina&#13;
inflammation</text>
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                <text>Warts are the most common lesions caused by human&#13;
papillomavirus (HPV). Recent research suggests that oxidative stress and inflammation are involved&#13;
in the pathogenesis of HPV-related lesions. It has been shown that the soluble receptor for advanced&#13;
glycation end products (sRAGE) may act as a protective factor against the deleterious effects of&#13;
inflammation and oxidative stress, two interconnected processes. However, in HPV infection, the role&#13;
of sRAGE, constitutively expressed in the skin, has not been investigated in previous studies. Materials&#13;
and Methods: In order to analyze the role of sRAGE in warts, we investigated the link between&#13;
sRAGE and the inflammatory response on one hand, and the relationship between sRAGE and the&#13;
total oxidant/antioxidant status (TOS/TAS) on the other hand, in both patients with palmoplantar&#13;
warts (n = 24) and healthy subjects as controls (n = 28). Results: Compared to the control group,&#13;
our results showed that patients with warts had lower levels of sRAGE (1036.50 ± 207.60 pg/mL&#13;
vs. 1215.32 ± 266.12 pg/mL, p &lt; 0.05), higher serum levels of TOS (3.17 ± 0.27 vs. 2.93 ± 0.22 μmol&#13;
H2O2 Eq/L, p &lt; 0.01), lower serum levels of TAS (1.85 ± 0.12 vs. 2.03 ± 0.14 μmol Trolox Eq/L, p &lt; 0.01)&#13;
and minor variations of the inflammation parameters (high sensitivity-CRP, interleukin-6, fibrinogen,&#13;
and erythrocyte sedimentation rate). Moreover, in patients with warts, sRAGE positively correlated&#13;
with TAS (r = 0.43, p &lt; 0.05), negatively correlated with TOS (r = −0.90, p &lt; 0.01), and there was no&#13;
significant correlation with inflammation parameters. There were no significant differences regarding&#13;
the studied parameters between groups when we stratified the patients according to the number of&#13;
the lesions and disease duration. Conclusions: Our results suggest that sRAGE acts as a negative&#13;
regulator of oxidative stress and could represent a mediator involved in the development of warts.&#13;
However, we consider that the level of sRAGE cannot be used as a biomarker for the severity of warts.&#13;
To the best of our knowledge, this is the first study to demonstrate that sRAGE could be involved in&#13;
HPV pathogenesis and represent a marker of oxidative stress in patients with warts.</text>
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                <text>Stefano Aquaro (Ed.)</text>
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                <text>https://www.mdpi.com/journal/medicina/special issues/human_viral infections</text>
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                <text>MDPI&#13;
St. Alban-Anlage 66&#13;
4052 Basel, Switzerland</text>
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                <text>Stefano Aquaro&#13;
J®F</text>
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                <text>ISBN 978-3-03943-917-1 (Hbk); ISBN 978-3-03943-918-8 (PDF)&#13;
https://doi.org/10.3390/books978-3-03943-918-8</text>
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